GPCRdb

CHEMBL1774063

Agent/drug
Bioactivity

CHEMBL1774063

SMILES	O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)nc2N1
InChIKey	VULDVDPDFZYFND-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	448.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.75	7.75	7.75	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	9.89	9.89	9.89	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.47	8.73	9.00	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	8.49	8.49	8.49	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL1774063

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.