CHEMBL161780


SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN3CC[C@@H](CNCc4ccccc4)C3)c2c1
InChIKey MGCUTECDFDAQCK-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.21 7.21 7.21 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 8.96 8.96 8.96 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.46 8.46 8.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.24 5.24 5.24 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 7.39 7.39 7.39 ChEMBL