CHEMBL178923


SMILES COc1cc2nc(N3CCN(C(=O)CCCCC4CCSS4)CC3)nc(N)c2cc1OC
InChIKey TZIDXYRBHBHFBV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.9 8.9 8.9 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.19 7.19 7.19 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.85 8.85 8.85 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.05 9.05 9.05 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 7.92 7.92 7.92 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 7.39 7.39 7.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database