CHEMBL1632158


SMILES COC(=O)CCCCCN1CCC(CNC(=O)c2c3n(c4ccccc24)CCCO3)CC1
InChIKey RNXYMZNGMNWKMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 441.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 9.97 9.97 9.97 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.9 5.9 5.9 ChEMBL
H2 HRH2 Human Histamine A pKi 5.5 5.5 5.5 ChEMBL
H1 HRH1 Human Histamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.6 5.6 5.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.2 5.2 5.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database