CHEMBL180060


SMILES O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(I)cc1
InChIKey QMKMSUCBVBINOY-OWOJBTEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 529.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.18 8.37 8.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.72 7.21 7.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.62 7.62 7.62 ChEMBL
D3 DRD3 Human Dopamine A pIC50 7.62 7.62 7.62 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.79 6.79 6.79 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.79 6.79 6.79 ChEMBL