CHEMBL163462


SMILES NC(=O)C(c1ccccc1)N1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1
InChIKey COARACZJPUUEKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 443.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 7.26 7.57 7.89 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pEC50 8.42 9.06 9.7 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 8.64 9.17 9.7 ChEMBL