CHEMBL1642116


SMILES CN1CCN(c2ccc3c(c2)N(S(=O)(=O)c2ccc4ccccc4c2)CCC3=O)CC1
InChIKey YLSBAGZHIBFNRL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.84 6.84 6.84 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.44 5.44 5.44 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 6.73 7.16 7.58 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 5.29 5.29 5.29 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.89 5.89 5.89 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.44 6.44 6.44 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.17 6.17 6.17 ChEMBL