CHEMBL1642117


SMILES CN1CCN(c2cccc3c2C(=O)CCN3S(=O)(=O)c2ccc3ccccc3c2)CC1
InChIKey TZMHJAWORUSIEG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.21 6.21 6.21 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.75 5.75 5.75 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.21 7.21 7.21 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.36 6.36 6.36 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.53 5.53 5.53 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.12 6.12 6.12 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.48 6.48 6.48 ChEMBL