CHEMBL1643778


SMILES CN([C@@H]1CCc2c(CC(=O)O)c3ccc(-c4ccccc4)cc3n2C1)S(=O)(=O)c1ccc(F)cc1
InChIKey LLOKGCTYZOPODZ-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 492.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Human Prostanoid A pKi 5.89 5.89 5.89 ChEMBL
DP2 PD2R2 Human Prostanoid A pKi 8.62 8.62 8.62 ChEMBL
TP TA2R Human Prostanoid A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP2 PD2R2 Human Prostanoid A pIC50 7.52 7.93 8.35 ChEMBL