CHEMBL1644003


SMILES Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-c3c(C(=O)N(C)C)sc4c(C)cc(C)cc34)cc2)cc1
InChIKey SBJWASMXBSBHSJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 549.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 5.48 5.48 5.48 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 6.28 6.28 6.28 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 8.59 8.9 9.27 ChEMBL
TP TA2R Human Prostanoid A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pIC50 8.92 8.92 8.92 ChEMBL