CHEMBL183434


SMILES NCc1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)CC1
InChIKey MJWHBKTUULEGMJ-KAYWLYCHSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 531.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 7.57 7.57 7.57 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.64 5.64 5.64 ChEMBL
MC3 MC3R Human Melanocortin A pKi 7.48 7.48 7.48 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 6.05 6.3 6.56 ChEMBL