GPCRdb

CHEMBL1829477

Agent/drug
Bioactivity

CHEMBL1829477

SMILES	C[C@@H]1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1F
InChIKey	YVXDOSIKSIZMGR-CQSZACIVSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	6
Molecular weight (Da)	345.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Rat	Histamine	A	pKi	7.57	7.57	7.57	ChEMBL
H₃	HRH3	Human	Histamine	A	pKi	8.24	8.24	8.24	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

H₃	HRH3	Human	Histamine	A	pEC50	8.89	8.89	8.89	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL1829477

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.