GPCRdb

CHEMBL184275

Agent/drug
Bioactivity

CHEMBL184275

SMILES	O=C(NCCc1ccc(Cl)cc1Cl)c1ccc(N/C(=N/C2CCCCC2)N2CCNCC2)cc1
InChIKey	YEXGHTGVNJDCFJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	6
Molecular weight (Da)	501.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	6.40	6.40	6.40	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	5.66	5.66	5.66	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	6.19	6.19	6.19	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	7.75	7.75	7.75	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Human	Melanocortin	A	pEC50	5.72	5.72	5.72	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pIC50	6.34	6.34	6.34	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL184275

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.