GPCRdb

CHEMBL186339

Agent/drug
Bioactivity

CHEMBL186339

SMILES	O=C(NCCc1ccc(Cl)cc1Cl)c1ccc(N/C(=N\C2CCNC2)NC2CCCCC2)cc1
InChIKey	PDXOBKQWULUDRV-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	4
Rotatable bonds	7
Molecular weight (Da)	501.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	5.72	5.72	5.72	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	5.60	5.60	5.60	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	5.82	5.82	5.82	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	7.58	7.58	7.58	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₅	MC5R	Human	Melanocortin	A	pIC50	6.28	6.28	6.28	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL186339

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.