CHEMBL1739656


SMILES O=C(Nc1ccc2[nH]nc(S(=O)(=O)c3cccc4ccccc34)c2c1)C1CCNCC1
InChIKey QQYRQLGIRAUMJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 434.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.48 7.48 7.48 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.09 8.09 8.09 ChEMBL