GPCRdb

CHEMBL191039

Agent/drug
Bioactivity

CHEMBL191039

SMILES	O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1ccccc1
InChIKey	AYVLYDAJDALPHK-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	339.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₅	GRM5	Rat	Metabotropic glutamate	C	pKi	5.38	5.38	5.38	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₅	GRM5	Rat	Metabotropic glutamate	C	pEC50	6.52	6.61	6.69	ChEMBL
mGlu₅	GRM5	Human	Metabotropic glutamate	C	pEC50	7.40	7.40	7.40	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL191039

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.