CHEMBL1774108


SMILES Cn1c(CN2CCC(c3ccc(C(F)(F)F)cc3)CC2)nc2ncccc21
InChIKey JJJUTEJMSCWLKG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.39 6.39 6.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.37 7.37 7.37 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 7.32 7.32 7.32 ChEMBL