6-Cl-MLT


SMILES COc1cc2c(CCNC(=O)C)c[nH]c2cc1Cl
InChIKey LUINDDOUWHRIPW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 266.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 7.9 8.55 9.2 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.4 9.6 9.8 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 9.7 9.7 9.7 ChEMBL
MT1 MTR1A Human Melatonin A pKi 7.94 7.94 7.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.05 6.8 8.55 ChEMBL