7α,25-dihydroxycholesterol


SMILES O[C@H]1CC[C@]2(C(=C[C@H]([C@@H]3[C@@H]2CC[C@]2([C@H]3CC[C@@H]2[C@@H](CCCC(O)(C)C)C)C)O)C1)C
InChIKey BQMSKLCEWBSPPY-IKVTXIKFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 418.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPR183 GP183 Human A orphans A pEC50 8.1 8.97 9.85 Guide to Pharmacology
GPR183 GP183 Human A orphans A pIC50 7.15 8.38 9.62 Guide to Pharmacology
GPR183 GP183 Human A orphans A pEC50 9.85 10.17 10.49 ChEMBL
GPR183 GP183 Rat A orphans A pEC50 8.88 8.88 8.88 ChEMBL
GPR183 GP183 Mouse A orphans A pEC50 9.15 9.15 9.15 ChEMBL