11-deoxy-PGE1


SMILES CCCCC[C@@H](/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)O)O
InChIKey DPNOTBLPQOITGU-LDDQNKHRSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Rat Prostanoid A pKi 8.5 8.5 8.5 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 8.82 8.82 8.82 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pKi 7.5 7.5 7.5 Guide to Pharmacology
EP4 PE2R4 Mouse Prostanoid A pKi 7.6 7.6 7.6 Guide to Pharmacology
EP2 PE2R2 Mouse Prostanoid A pKi 7.3 7.3 7.3 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 8.9 8.9 8.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 9.33 9.33 9.33 Guide to Pharmacology