ACTH


SMILES None
InChIKey IDLFZVILOHSSID-OVLDLUHVSA-N
Sequence SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 8GY7
Ligand site mutations CRF1

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 8.6 8.6 8.6 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKi 7.06 7.06 7.06 Guide to Pharmacology
MC5 MC5R Human Melanocortin A pKi 5.0 5.0 5.0 Guide to Pharmacology
MC3 MC3R Human Melanocortin A pKi 8.15 8.15 8.15 Drug Central
MC2 ACTHR Mouse Melanocortin A pKd 8.01 8.01 8.01 Drug Central
MC1 MSHR Human Melanocortin A pKi 8.07 8.07 8.07 Drug Central
MC4 MC4R Human Melanocortin A pKi 8.21 8.21 8.21 Drug Central
MC4 MC4R Human Melanocortin A pKi 6.16 6.16 6.16 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database