ACTH-(1-24)


SMILES None
InChIKey ZOEFCCMDUURGSE-SQKVDDBVSA-N
Sequence SYSMEHFRWGKPVGKKRRPVKVYP

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations MC4

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC2 ACTHR Mouse Melanocortin A pKd 9.1 9.1 9.1 Guide to Pharmacology
MC2 ACTHR Human Melanocortin A pKi 8.08 8.08 8.08 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 8.04 8.04 8.04 Drug Central
MC4 MC4R Human Melanocortin A pEC50 9.19 9.19 9.19 ChEMBL