AL-37350A


SMILES C[C@@H](Cc1c[nH]c2c1c1CCCOc1cc2)N
InChIKey VVHJUSGIUWQPIT-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.5 8.5 8.5 Guide to Pharmacology
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.28 8.28 8.28 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.47 8.47 8.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.48 5.48 5.48 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pIC50 4.72 4.72 4.72 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 4.85 4.85 4.85 ChEMBL