CHEMBL1813287


SMILES CCN1c2ccccc2C[C@@H]1COc1ccc(C(=O)n2c(C)c(CC(=O)O)c3ccccc32)c(C)c1
InChIKey VAIYPASGHXDISO-JOCHJYFZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 482.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Mouse Prostanoid A pKi 5.85 5.85 5.85 ChEMBL
DP1 PD2R Mouse Prostanoid A pKi 8.32 8.32 8.32 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 5.57 5.57 5.57 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 5.8 5.8 5.8 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.55 5.55 5.55 ChEMBL
IP PI2R Human Prostanoid A pKi 5.66 5.66 5.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 8.66 8.66 8.66 ChEMBL
TP TA2R Human Prostanoid A pIC50 5.12 5.12 5.12 ChEMBL