α-helical CRF
| SMILES | None |
| InChIKey | TYEPJUPPTULOKD-GVKLFNHCSA-N |
| Sequence | DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKd | 7.3 | 7.55 | 7.8 | Guide to Pharmacology |
| CRF2 | CRFR2 | Mouse | Corticotropin-releasing factor | B1 | pKd | 9.0 | 9.05 | 9.1 | Guide to Pharmacology |
| CRF2 | CRFR2 | Rat | Corticotropin-releasing factor | B1 | pKd | 8.3 | 8.35 | 8.4 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |