CHEMBL1819622


SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(=O)O)ccc3Cl)c(Cl)c2)Oc2ccccc21
InChIKey UQHKLJCYYLWRGF-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 500.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pKi 7.89 7.89 7.89 ChEMBL
EP1 PE2R1 Mouse Prostanoid A pKi 5.18 5.18 5.18 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 7.36 7.36 7.36 ChEMBL
IP PI2R Human Prostanoid A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
DP1 PD2R Mouse Prostanoid A pIC50 8.37 8.37 8.37 ChEMBL