CHEMBL197442


SMILES COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1cccc([N+](=O)[O-])c1
InChIKey ORFCLRGEMAZVIP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 14
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 9.1 9.1 9.1 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.5 9.5 9.5 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 10.2 10.2 10.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.68 7.68 7.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database