angiotensin II


SMILES None
InChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
Sequence DRVYIHPF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 6OS0 6JOD

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Human Angiotensin A pKd 10.2 10.2 10.2 Guide to Pharmacology
AT1 AGTRA Rat Angiotensin A pKi 9.02 9.02 9.02 PDSP Ki database
AT2 AGTR2 Human Angiotensin A pKd 7.99 7.99 7.99 Drug Central
AT1 AGTRB Rat Angiotensin A pKi 8.02 8.02 8.02 Drug Central
AT1 AGTR1 Human Angiotensin A pKi 9.05 9.44 9.8 ChEMBL
AT1 AGTR1 Human Angiotensin A pKd 8.7 8.7 8.7 ChEMBL
AT2 AGTR2 Human Angiotensin A pKi 8.92 9.48 9.7 ChEMBL
AT1 AGTR1 Bovine Angiotensin A pKd 8.08 8.08 8.08 Drug Central
AT1 AGTR1 Bovine Angiotensin A pKd 8.24 8.24 8.24 ChEMBL
AT1 AGTRB Rat Angiotensin A pKi 9.02 9.27 9.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTR1 Human Angiotensin A pIC50 9.0 9.15 9.3 Guide to Pharmacology
AT1 AGTRA Rat Angiotensin A pIC50 8.03 8.03 8.03 Drug Central
AT1 AGTR1 Human Angiotensin A pIC50 8.03 8.03 8.03 Drug Central
AT1 AGTR1 Human Angiotensin A pIC50 7.99 8.57 9.14 ChEMBL
AT1 AGTR1 Human Angiotensin A pEC50 8.01 8.8 9.31 ChEMBL
AT2 AGTR2 Human Angiotensin A pIC50 8.6 9.3 10.1 ChEMBL
AT1 AGTRB Rat Angiotensin A pIC50 9.4 9.4 9.4 ChEMBL
AT1 AGTRA Rat Angiotensin A pEC50 8.17 8.53 8.89 ChEMBL
AT1 AGTRA Rat Angiotensin A pIC50 9.4 9.4 9.4 ChEMBL