GPCRdb

CHEMBL1085672

Agent/drug
Bioactivity

CHEMBL1085672

SMILES	O=C1N(CC2CCCCN2)CCN1c1cccc(Cl)c1
InChIKey	HVSRNYNPOUFDNJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	293.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1B	ADA1B	Human	Adrenoceptors	A	pKi	6.50	6.50	6.50	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.80	5.80	5.80	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.10	7.10	7.10	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.40	8.40	8.40	ChEMBL
H₁	HRH1	Human	Histamine	A	pKi	5.70	5.70	5.70	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	6.10	6.10	6.10	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pEC50	6.30	6.30	6.30	ChEMBL
D₂	DRD2	Human	Dopamine	A	pEC50	9.20	9.20	9.20	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL1085672

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.