arpromidine


SMILES NC(=NCCCc1[nH]cnc1)NCCC(c1ccccn1)c1ccc(cc1)F
InChIKey KZZIVOLMJPSDEP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 9
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.5 6.5 6.5 Guide to Pharmacology
H2 HRH2 Human Histamine A pKi 6.3 7.15 8.0 Guide to Pharmacology
H1 HRH1 Human Histamine A pKi 6.45 6.45 6.45 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKi 7.48 7.48 7.48 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKd 7.65 7.65 7.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database