CHEMBL184275


SMILES O=C(NCCc1ccc(Cl)cc1Cl)c1ccc(N/C(=N/C2CCCCC2)N2CCNCC2)cc1
InChIKey YEXGHTGVNJDCFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 501.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.4 6.4 6.4 ChEMBL
MC5 MC5R Human Melanocortin A pKi 7.75 7.75 7.75 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.66 5.66 5.66 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.19 6.19 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pIC50 6.34 6.34 6.34 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.72 5.72 5.72 ChEMBL