CHEMBL1852341


SMILES Cc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c(C)n1-c1ccccc1
InChIKey JXNOGBVEQNMHDF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 485.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 7.96 7.96 7.96 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 6.87 6.87 6.87 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.31 6.31 6.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.73 7.73 7.73 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.31 8.31 8.31 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.86 5.86 5.86 ChEMBL