CHEMBL1852516


SMILES Cc1nc(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)c(C)n1-c1ccccc1
InChIKey QDRMTYQLXZSORG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 8.17 8.17 8.17 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.4 5.4 5.4 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 5.77 5.77 5.77 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 7.18 7.18 7.18 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.66 5.66 5.66 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.51 7.51 7.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.41 8.41 8.41 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.04 6.04 6.04 ChEMBL