CHEMBL186083


SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1
InChIKey GRAFEEBFOIOLGS-AREMUKBSSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 12
Molecular weight (Da) 553.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.89 5.89 5.89 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.0 6.0 6.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.85 5.92 6.0 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.68 7.68 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database