CHEMBL186630


SMILES N[C@@]1(C(=O)O)[C@H](OCc2ccc(F)c(F)c2)C[C@@H]2[C@H]1[C@@]2(F)C(=O)O
InChIKey MRMHYXQUHGBUJY-JAGWWQSPSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 345.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Rat Metabotropic glutamate C pKi 8.52 8.52 8.52 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pIC50 7.39 7.39 7.39 ChEMBL