BAY-6672


SMILES OC(=O)CC[C@H](c1ccccc1Cl)CNC(=O)c1c(C)c(nc2c1cc(Br)cc2)N1CCCC1
InChIKey YQOLEILXOBUDMU-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 543.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pKi 7.8 7.8 7.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FP PF2R Human Prostanoid A pIC50 7.66 7.66 7.66 Guide to Pharmacology
FP PF2R Rat Prostanoid A pIC50 7.28 7.62 7.96 ChEMBL
FP PF2R Human Prostanoid A pIC50 7.66 7.81 7.96 ChEMBL
TP TA2R Human Prostanoid A pIC50 5.66 5.66 5.66 ChEMBL
FP PF2R Mouse Prostanoid A pIC50 7.75 7.83 7.92 ChEMBL