CHEMBL187746


SMILES Fc1cc(-c2ccncc2)cc(-n2nnc(-c3ccccn3)n2)c1
InChIKey YBZAHQMKDFUBLV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 318.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.02 6.02 6.02 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.09 6.09 6.09 ChEMBL