TROSPIUM


SMILES O=C(O[C@@H]1C[C@@H]2CC[C@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1
InChIKey OYYDSUSKLWTMMQ-JKHIJQBDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 392.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.99 8.99 8.99 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.94 8.94 8.94 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.46 8.46 8.46 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.84 8.84 8.84 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database