CHEMBL189118


SMILES Cc1cc(N(C)CCN(C)C)nc2ccc(NC(=O)/C=C/c3ccc(OC(F)(F)F)cc3)cc12
InChIKey RVSLLQIPFFIMSB-KPKJPENVSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 472.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 6.1 6.1 6.1 ChEMBL
H2 HRH2 Human Histamine A pIC50 6.07 6.07 6.07 ChEMBL
MCH1 MCHR1 Human Melanin-concentrating hormone A pIC50 6.84 7.58 7.8 ChEMBL
D1 DRD1 Human Dopamine A pIC50 6.05 6.05 6.05 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 6.32 6.32 6.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.05 6.05 6.05 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 5.89 5.89 5.89 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.64 5.64 5.64 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 5.72 5.72 5.72 ChEMBL