CHEMBL2031885


SMILES C[C@@H]1CCCN1CCN1CCc2cc(-c3ccc(C(=O)N4CCCC4)cc3)ccc2C1=O
InChIKey SPKOQCHHYOCMGR-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 431.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.06 5.06 5.06 ChEMBL
H3 HRH3 Human Histamine A pKi 9.7 9.7 9.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.91 4.91 4.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database