CHEMBL1910140


SMILES COc1ccccc1N1CCN(CCN(C(=O)C23CCC(CF)(CC2)CC3)c2ccccn2)CC1
InChIKey WAEVDDXBNJUJNE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 480.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.14 7.14 7.14 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.13 7.13 7.13 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.96 9.07 9.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.81 8.81 8.81 ChEMBL