BMS-986141
| SMILES | COc1nn2cc(nc2s1)c1cc2c(o1)cc(OC)cc2OCc1csc(n1)c1ccc(cc1)C(=O)N(C)C |
| InChIKey | KEEBLYWBELVGPQ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 11 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 8 |
| Molecular weight (Da) | 561.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | Yes |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAR4 | PAR4 | Human | Proteinase-activated | A | pKd | 10.0 | 10.04 | 10.07 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| PAR4 | PAR4 | Human | Proteinase-activated | A | pIC50 | 9.3 | 9.3 | 9.3 | Guide to Pharmacology |
| PAR4 | PAR4 | Human | Proteinase-activated | A | pIC50 | 8.47 | 8.85 | 9.4 | ChEMBL |
| PAR4 | PAR4 | Human | Proteinase-activated | A | pEC50 | 9.35 | 9.35 | 9.35 | ChEMBL |