GPCRdb

CHEMBL2036324

Agent/drug
Bioactivity

CHEMBL2036324

SMILES	O=C(O)c1csc(SCCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2cccc(-c3nc4ccccc4s3)c2)n1
InChIKey	LHSFFQORRGHKSR-BJIJGURPSA-N

Chemical Properties

Hydrogen bond acceptors	8
Hydrogen bond donors	2
Rotatable bonds	10
Molecular weight (Da)	551.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Mouse	Prostanoid	A	pKi	5.10	5.10	5.10	ChEMBL
EP₂	PE2R2	Mouse	Prostanoid	A	pKi	7.82	7.82	7.82	ChEMBL
EP₄	PE2R4	Mouse	Prostanoid	A	pKi	9.72	9.72	9.72	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Rat	Prostanoid	A	pEC50	5.57	5.57	5.57	ChEMBL
EP₄	PE2R4	Rat	Prostanoid	A	pEC50	7.89	7.89	7.89	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL2036324

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.