GPCRdb

BW723C86

Agent/drug
Bioactivity

BW723C86

SMILES	CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12
InChIKey	ALFGDCNSEBJYSP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	5
Molecular weight (Da)	286.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	6.19	6.19	6.19	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pKi	6.40	6.40	6.40	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	7.20	7.20	7.20	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.30	7.95	8.60	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.29	7.29	7.29	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.90	7.00	7.10	Guide to Pharmacology
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	6.97	6.97	6.97	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	6.53	6.53	6.53	ChEMBL

Showing 1 to 8 of 8 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pIC50	5.95	5.95	5.95	ChEMBL
5-HT_1B	5HT1B	Rat	5-Hydroxytryptamine	A	pIC50	6.38	6.38	6.38	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pIC50	7.09	7.09	7.09	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pIC50	6.69	6.69	6.69	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pIC50	6.19	6.19	6.19	ChEMBL

Showing 1 to 5 of 5 entries

BW723C86

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids GPCRdb

Compound is not listed as a drug.