GPCRdb

CHEMBL2057452

Agent/drug
Bioactivity

CHEMBL2057452

SMILES	COc1cc2c(cc1OC)C1Cc3cc(C)cc(C)c3CN1CC2
InChIKey	BEZZGCHAIFWOPE-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	323.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pKi	5.84	5.84	5.84	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pIC50	5.54	5.54	5.54	ChEMBL
D₂	DRD2	Human	Dopamine	A	pEC50	4.81	4.81	4.81	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL2057452

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.