cicaprost


SMILES CCC#CC[C@@H]([C@@H](C#C[C@H]1[C@H](O)C[C@H]2[C@@H]1C/C(=C/COCC(=O)O)/C2)O)C
InChIKey ARUGKOZUKWAXDS-SEWALLKFSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 5.9 5.9 5.9 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 6.59 6.59 6.59 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 7.4 7.4 7.4 Guide to Pharmacology
IP PI2R Human Prostanoid A pKi 7.8 7.8 7.8 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 6.77 6.77 6.77 Guide to Pharmacology
IP PI2R Mouse Prostanoid A pKi 8.0 8.0 8.0 Guide to Pharmacology
EP2 PE2R2 Mouse Prostanoid A pKi 5.9 5.9 5.9 Guide to Pharmacology
EP3 PE2R3 Mouse Prostanoid A pKi 6.77 6.77 6.77 PDSP Ki database
IP PI2R Mouse Prostanoid A pKi 8.0 8.0 8.0 PDSP Ki database
EP2 PE2R2 Mouse Prostanoid A pKi 5.89 5.89 5.89 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 5.87 5.87 5.87 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 6.59 6.59 6.59 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 5.87 6.62 7.36 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.87 5.87 5.87 PDSP Ki database
IP PI2R Human Prostanoid A pKi 7.77 7.77 7.77 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 8.23 8.23 8.23 Drug Central
EP1 PE2R1 Human Prostanoid A pKi 8.23 8.23 8.23 Drug Central
EP3 PE2R3 Human Prostanoid A pKi 8.18 8.18 8.18 Drug Central
EP4 PE2R4 Human Prostanoid A pKi 8.13 8.13 8.13 Drug Central
FP PF2R Human Prostanoid A pKi 8.23 8.23 8.23 Drug Central
IP PI2R Human Prostanoid A pKi 8.11 8.11 8.11 Drug Central
EP3 PE2R3 Mouse Prostanoid A pKi 8.17 8.17 8.17 Drug Central
IP PI2R Mouse Prostanoid A pKi 8.1 8.1 8.1 Drug Central
EP2 PE2R2 Mouse Prostanoid A pKi 8.23 8.23 8.23 Drug Central
FP PF2R Human Prostanoid A pKi 5.87 5.87 5.87 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database