CHEMBL2089156


SMILES C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1
InChIKey SEKAQUSPSDPIAN-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 244.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.39 6.39 6.39 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.56 6.56 6.56 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.38 7.38 7.38 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.8 5.8 5.8 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 8.7 8.7 8.7 ChEMBL