cannabinol


SMILES CCCCCc1cc(O)c2c(c1)OC(c1c2cc(C)cc1)(C)C
InChIKey VBGLYOIFKLUMQG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 6.0 6.25 6.5 Guide to Pharmacology
CB1 CNR1 Rat Cannabinoid A pKi 6.41 6.54 6.67 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 6.52 7.08 7.8 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 5.96 6.88 7.89 ChEMBL
CB1 CNR1 Rat Cannabinoid A pKi 6.51 6.51 6.51 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pEC50 6.5 6.71 6.92 ChEMBL
CB2 CNR2 Human Cannabinoid A pEC50 6.58 6.86 7.14 ChEMBL
CB1 CNR1 Human Cannabinoid A pEC50 7.12 7.12 7.12 ChEMBL