CHEMBL210567


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccc2CCc2ccc(cc2)CC3)CC1
InChIKey ZKXPPFSIRYLWQE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 497.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.66 5.66 5.66 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.17 6.17 6.17 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.18 6.24 6.31 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.96 8.08 8.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.24 7.42 7.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.52 9.18 9.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.62 7.88 8.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database