CHEMBL196598


SMILES COc1ccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cc3)CC2)cc1N1CCN(C)CC1
InChIKey DZKYLEMMURXALW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 477.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.55 7.55 7.55 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.21 6.21 6.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database